XLO: Xilio Therapeutics insider trading, 5% holders and institutional ownership

From public SEC filings: open-market insider purchases and sales (Form 4, last 180 days), holders of 5% or more (Schedules 13D and 13G) and institutional ownership (Form 13F). Insider and 5% data delayed 48 hours.

Insider trading

0 open-market buys totaling - and 0 sales totaling - in the last 180 days.

Activist and 5% holders

FiledWhatHolderStakeChangeFiling
2026-08-1413G amendmentStemPoint Capital LP9.50%SEC

Institutional ownership (Q2 2026)

26 institutions reported holding $26.28M of Xilio Therapeutics on Form 13F (23 the quarter before). 11 opened a new position and 7 sold out. Shares held by institutions: +41%.

Largest holdersSharesValue
Bain Capital Life Sciences Investors, LLC664,021$6.36M
ORBIMED ADVISORS LLC592,300$5.67M
Frazier Life Sciences Management, L.P.422,505$4.05M
Stonepine Capital Management, LLC225,994$2.17M
VANGUARD CAPITAL MANAGEMENT LLC178,517$1.71M
Sio Capital Management, LLC152,464$1.46M
ADAGE CAPITAL PARTNERS GP, L.L.C.111,541$1.07M
Merck & Co., Inc.105,982$1.02M
RENAISSANCE TECHNOLOGIES LLC64,153$615K
MORGAN STANLEY56,954$546K

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