RHHBY: Roche Holding insider trading, 5% holders and institutional ownership

From public SEC filings: open-market insider purchases and sales (Form 4, last 180 days), holders of 5% or more (Schedules 13D and 13G) and institutional ownership (Form 13F). Insider and 5% data delayed 48 hours.

Insider trading

0 open-market buys totaling - and 0 sales totaling - in the last 180 days.

Institutional ownership (Q2 2026)

70 institutions reported holding $251.77M of Roche Holding on Form 13F (68 the quarter before). 11 opened a new position and 11 sold out. Shares held by institutions: -4%.

Largest holdersSharesValue
Aristotle Capital Management, LLC1,970,729$101.33M
Saratoga Research & Investment Management1,188,687$61.04M
Boston Common Asset Management, LLC300,155$15.41M
OLD NATIONAL BANCORP /IN/287,612$14.83M
Altrius Capital Management Inc190,302$9.77M
Moran Wealth Management, LLC173,426$8.91M
HUNTINGTON NATIONAL BANK117,499$6.06M
RHUMBLINE ADVISERS98,640$5.07M
KORNITZER CAPITAL MANAGEMENT INC /KS61,873$3.19M
Sterling Capital Management LLC60,290$3.11M

Clinical trial readouts

Up to 20 Phase 2 or 3 trials by Roche Holding with a primary completion date in the last 90 days or the next 12 months and no results posted yet, from ClinicalTrials.gov. (est.) = company estimate.

Primary completionDrugConditionPhasePatientsStatusTrial
2026-08-13CrovalimabParoxysmal Hemoglobinuria, NocturnalPhase 1/259CompletedNCT03157635
2026-08-25GiredestrantEndometrial CancerPhase 233CompletedNCT05634499
2026-08-25ZifibancimigMacular DegenerationPhase 1/2177CompletedNCT04567303
2026-09-03RO7204239ObesityPhase 2285Enrollment completeNCT06965413
2026-09-17Ocrelizumab Test FormulationMultiple SclerosisPhase 2193Enrollment completeNCT07074886
2026-09-30 (est.)EntrectinibCarcinoma, Non-Small-Cell LungPhase 3217Enrollment completeNCT04603807
2026-10-08 (est.)TobemstomigRenal Cell CarcinomaPhase 2199Enrollment completeNCT05805501
2026-10-14 (est.)AtezolizumabUnresectable Hepatocellular CarcinomaPhase 3557Enrollment completeNCT04770896
2026-10-16 (est.)89Zr-Df-IAB22M2CNon-Hodgkins LymphomaPhase 1/2211Enrollment completeNCT03533283
2026-10-19 (est.)TobemstomigBreast CancerPhase 283Enrollment completeNCT05852691
2026-10-22 (est.)OcrelizumabProgressive Multiple Sclerosis (PMS)Phase 3927Enrollment completeNCT03523858
2026-10-28 (est.)RO7204239Spinal Muscular Atrophy (SMA)Phase 2/397Enrollment completeNCT05115110
2026-10-29 (est.)AfimkibartModerately to Severely Active Ulcerative ColitisPhase 3350Enrollment completeNCT06588855
2026-10-31 (est.)VenetoclaxChronic Lymphocytic LeukemiaPhase 2118Enrollment completeNCT06524375
2026-11-13 (est.)InavolisibBreast CancerPhase 3420RecruitingNCT05646862
2026-11-18 (est.)SatralizumabDuchenne Muscular DystrophyPhase 230Enrollment completeNCT06450639
2026-11-19 (est.)RO7269162Alzheimer's DiseasePhase 2256Enrollment completeNCT06402838
2026-11-30 (est.)AtezolizumabCancerPhase 3382Enrollment completeNCT03148418
2026-11-30 (est.)AlectinibNon-small Cell Lung CancerPhase 299RecruitingNCT04302025
2026-12-16 (est.)SatralizumabNMDAR Autoimmune EncephalitisPhase 3122Enrollment completeNCT05503264

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