OPK: Opko Health, Inc. insider trading, 5% holders and institutional ownership

From public SEC filings: open-market insider purchases and sales (Form 4, last 180 days), holders of 5% or more (Schedules 13D and 13G) and institutional ownership (Form 13F). Insider and 5% data delayed 48 hours.

Insider trading

0 open-market buys totaling - and 0 sales totaling - in the last 180 days.

Institutional ownership (Q2 2026)

223 institutions reported holding $302.75M of Opko Health, Inc. on Form 13F (236 the quarter before). 21 opened a new position and 31 sold out. Shares held by institutions: +1%.

Largest holdersSharesValue
Rubric Capital Management LP47,791,243$71.69M
BlackRock, Inc.36,978,893$55.47M
VANGUARD CAPITAL MANAGEMENT LLC14,968,930$22.45M
VANGUARD PORTFOLIO MANAGEMENT LLC14,934,924$22.40M
GEODE CAPITAL MANAGEMENT, LLC11,581,027$17.38M
STATE STREET CORP10,309,070$15.46M
GOLDMAN SACHS GROUP INC7,035,492$10.55M
UBS Group AG5,006,284$7.51M
Whitefort Capital Management, LP4,511,412$6.77M
NORTHERN TRUST CORP3,756,163$5.63M

Clinical trial readouts

1 Phase 2 or 3 trials by Opko Health, Inc. with a primary completion date in the last 90 days or the next 12 months and no results posted yet, from ClinicalTrials.gov. (est.) = company estimate.

Primary completionDrugConditionPhasePatientsStatusTrial
2027-10 (est.)CTAP101CKD Stage 3Phase 240RecruitingNCT07494045

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