IONS: Ionis Pharmaceuticals Inc insider trading, 5% holders and institutional ownership

From public SEC filings: open-market insider purchases and sales (Form 4, last 180 days), holders of 5% or more (Schedules 13D and 13G) and institutional ownership (Form 13F). Insider and 5% data delayed 48 hours.

Insider trading

0 open-market buys totaling - and 2 sales totaling $61K in the last 180 days.

Insider sales

Trade dateInsiderRoleValue10b5-1 plan
2026-10-16Devers Shannon L.Officer$59K
2026-10-16Swayze EricOfficer$2K

Institutional ownership (Q2 2026)

516 institutions reported holding $13.52B of Ionis Pharmaceuticals Inc on Form 13F (499 the quarter before). 62 opened a new position and 46 sold out. Shares held by institutions: +4%.

Largest holdersSharesValue
FMR LLC24,631,956$1.95B
Capital World Investors21,669,226$1.72B
BlackRock, Inc.10,704,660$848.77M
VANGUARD PORTFOLIO MANAGEMENT LLC7,859,529$623.18M
WELLINGTON MANAGEMENT GROUP LLP7,651,415$606.68M
VANGUARD CAPITAL MANAGEMENT LLC7,211,497$571.80M
TWO SIGMA INVESTMENTS, LP6,252,342$495.75M
ROYAL BANK OF CANADA6,182,479$490.21M
STATE STREET CORP4,334,848$343.71M
GEODE CAPITAL MANAGEMENT, LLC3,584,024$294.75M

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