DFTX: Definium Therapeutics, Inc. insider trading, 5% holders and institutional ownership
From public SEC filings: open-market insider purchases and sales (Form 4, last 180 days), holders of 5% or more (Schedules 13D and 13G) and institutional ownership (Form 13F). Insider and 5% data delayed 48 hours.
Insider trading
0 open-market buys totaling - and 5 sales totaling $2.30M in the last 180 days.
Insider sales
| Trade date | Insider | Role | Value | 10b5-1 plan |
|---|---|---|---|---|
| 2026-09-25 | Karlin Daniel | Officer | $397K | yes |
| 2026-09-25 | Barrow Robert | CEO | $1.15M | yes |
| 2026-09-25 | Wiley Matthew T. | Officer | $113K | yes |
| 2026-09-25 | Sullivan Mark | Officer | $514K | yes |
| 2026-09-25 | Roberts Brandi | CFO | $123K | yes |
Activist and 5% holders
| Filed | What | Holder | Stake | Change | Filing |
|---|---|---|---|---|---|
| 2026-08-14 | Fell below 5% | Commodore Capital LP | 1.80% | SEC | |
| 2026-08-14 | 13G amendment | DRIEHAUS CAPITAL MANAGEMENT LLC | 5.36% | SEC |
Institutional ownership (Q2 2026)
362 institutions reported holding $5.11B of Definium Therapeutics, Inc. on Form 13F (245 the quarter before). 144 opened a new position and 29 sold out. Shares held by institutions: +47%.
| Largest holders | Shares | Value |
|---|---|---|
| BlackRock, Inc. | 11,232,834 | $528.39M |
| Avoro Capital Advisors LLC | 7,188,888 | $338.17M |
| Driehaus Capital Management LLC | 6,845,276 | $322.00M |
| Jupiter Topco LLC | 5,615,645 | $264.00M |
| Capital World Investors | 5,367,723 | $252.50M |
| FMR LLC | 4,752,921 | $223.58M |
| GEODE CAPITAL MANAGEMENT, LLC | 3,644,813 | $171.48M |
| STATE STREET CORP | 3,065,390 | $144.20M |
| Capital International Investors | 2,963,410 | $139.40M |
| Octagon Capital Advisors LP | 2,950,000 | $138.77M |
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