CRSP: CRISPR Therapeutics AG insider trading, 5% holders and institutional ownership

From public SEC filings: open-market insider purchases and sales (Form 4, last 180 days), holders of 5% or more (Schedules 13D and 13G) and institutional ownership (Form 13F). Insider and 5% data delayed 48 hours.

Insider trading

0 open-market buys totaling - and 6 sales totaling $4.10M in the last 180 days.

Insider sales

Trade dateInsiderRoleValue10b5-1 plan
2026-10-19Kulkarni SamarthCEO$2.38M
2026-10-14George SimeonDirector$720Kyes
2026-10-14Kasinger James R.Officer$51K
2026-10-14Kulkarni SamarthCEO$202K
2026-10-06Kasinger James R.Officer$119Kyes
2026-09-22Kasinger James R.Officer$626Kyes

Activist and 5% holders

FiledWhatHolderStakeChangeFiling
2026-08-1413G amendmentORBIS INVESTMENT MANAGEMENT LTD5.60%SEC
2026-07-2713G amendmentBlackRock, Inc.8.30%SEC

Institutional ownership (Q2 2026)

526 institutions reported holding $4.01B of CRISPR Therapeutics AG on Form 13F (494 the quarter before). 75 opened a new position and 47 sold out. Shares held by institutions: -1%.

Largest holdersSharesValue
ARK Investment Management LLC9,460,939$516.00M
BlackRock, Inc.8,348,977$455.35M
Orbis Allan Gray Ltd5,449,161$297.20M
Capital World Investors4,749,525$259.04M
STATE STREET CORP4,321,666$235.70M
GSK plc3,220,627$175.65M
GEODE CAPITAL MANAGEMENT, LLC2,509,915$136.92M
SR One Capital Management, LP2,038,763$111.19M
TWO SIGMA INVESTMENTS, LP1,988,621$108.46M
FMR LLC1,908,503$104.09M

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