AMLX: Amylyx Pharmaceuticals Inc insider trading, 5% holders and institutional ownership

From public SEC filings: open-market insider purchases and sales (Form 4, last 180 days), holders of 5% or more (Schedules 13D and 13G) and institutional ownership (Form 13F). Insider and 5% data delayed 48 hours.

Insider trading

0 open-market buys totaling - and 1 sales totaling $831K in the last 180 days.

Insider sales

Trade dateInsiderRoleValue10b5-1 plan
2026-10-05Milne George M JrDirector$831Kyes

Institutional ownership (Q2 2026)

206 institutions reported holding $2.06B of Amylyx Pharmaceuticals Inc on Form 13F (171 the quarter before). 47 opened a new position and 13 sold out. Shares held by institutions: +1%.

Largest holdersSharesValue
FMR LLC16,727,909$300.43M
BlackRock, Inc.8,827,085$158.53M
PERCEPTIVE ADVISORS LLC8,334,882$149.69M
TCG Crossover Management, LLC6,243,812$112.14M
Commodore Capital LP5,650,000$101.47M
Jupiter Topco LLC5,236,102$94.01M
Saturn V Capital Management LP4,624,101$83.05M
VANGUARD CAPITAL MANAGEMENT LLC4,224,224$75.87M
MORGAN STANLEY3,130,808$56.23M
Driehaus Capital Management LLC3,036,970$54.54M

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